 |
|
|
 |
30 Nov 2018
Curry spice boosts exercise performance in mice with heart failure
BY
Jane Kitchen
|
The research suggested that curcumin could be used to improve exercise capacity and prevent heart failure
New research suggests that curcumin, a main ingredient in curry, may improve exercise intolerance related to heart failure. The study is published ahead of print in the Journal of Applied Physiology. Curcumin, a chemical that comes from the turmeric plant, has been used as a traditional Asian medicine for centuries, primarily to treat gastrointestinal ailments and skin wounds. Studies increasingly suggest that the compound may prevent or limit muscle wasting associated with a number of health conditions, including heart failure.
People with heart failure have a reduced function of the left ventricle – the chamber of the heart that pumps blood out to the rest of the body – called reduced ejection fraction. A decreased ability to exercise (exercise intolerance) is another significant characteristic of heart failure.
Researchers from the University of Nebraska Medical Center in the US examined the effects of curcumin on a mouse model of heart failure with reduced ejection fraction.
One group of mice with heart failure received daily doses of curcumin for 12 weeks, and another group did not receive treatment. The heart failure groups were compared to a control group of healthy mice that received curcumin and an untreated control group.
The research team measured the exercise capacity of all the mice before and after curcumin treatment. The researchers also examined muscle fiber samples to assess enzyme expression levels. They found that expression of Nrf2 – a protein that regulates the expression of antioxidant enzymes – increased, and levels of antioxidant enzymes improved in the animals with heart failure that were given curcumin.
In addition, both groups that received curcumin – even the animals without heart failure – had improved exercise capacity when compared with the untreated groups, suggesting the effects of curcumin on skeletal muscle is not exclusive to heart failure.
"These data suggest that activation of Nrf2 in skeletal muscle may represent a novel therapeutic strategy to improve ... quality of life" in people with heart failure with reduced ejection fraction, the researchers wrote.
 |
|
|
|
|
|
|
|
|
|
Connect with
World Leisure |
|
|
|
|
|
|
|
|
|
|
|
|
|
| News headlines |
|
|
 |
 |
|
19 Apr 2024
The HCM team were busy at the recent FIBO Global Fitness event in Cologne, Germany, distributing a special FIBO edition of HCM in
.... more>> |
|
|
|
 |
|
18 Apr 2024
Atlanta-based boutique fitness software company, Xplor Mariana Tek, has kicked off a push for international expansion with a move into the UK market.
.... more>> |
|
|
|
 |
|
18 Apr 2024
The Global Wellness Institute (GWI) has released new data on the US’ wellness economy, valuing it at US$1.8 trillion. According to the
.... more>> |
|
|
|
 |
|
17 Apr 2024
Remedy Place, a US-based social wellness club brand, is poised for steady expansion in the coming years, with plans to open two new clubs annually
.... more>> |
|
|
|
|
|
 |
|
| Company profile |
|
Life Fitness
The Life Fitness family of brands offers an unrivalled product portfolio, providing customers with access to tailored solutions they need to target every segment of the fitness market.
View full profile>> |
|
| Catalogue gallery |
|
|
| Featured Supplier |
|
 |
|
|
|
in this issue
• Virgin gets right to wipe out rent arrears
• Fitness industry mourns passing of Jan Spaticchia
• STA offers mindfulness resources
|
|
|
|
|
|
|
 |
| World Leisure jobs |
 |
Centre Manager
Salary: £40,221 - £42,403pa + pension + benefits
Location: Exeter, UK
Company: Exeter City Council
|
|
Director of Operations
Salary: £61,000 - £64,000 + exceptional pension + excellent benefits
Location: Luton, UK
Company: Active Luton
|
|
|
|
|
|
| Diary dates |
|
| Powered
by leisurediary.com |
 |
|
|
|
|
